Multiple Myeloma Kappa Light Chain

Learn more about kappa and lambda light chains and multiple myeloma.

Multiple myeloma kappa light chain.

This means type g immunoglobulin one of the possible types of heavy chain one combination of types of light chain kappa or lambda. Each of these immunoglobulins have a light chain like kappa or lambda and a heavy chain like igg iga igm etc. The five types of heavy protein chains are g a d e and m. There are different stages and varieties of this incurable form of cancer and each one produces different symptoms and levels of risk to the patients well being and life.

These types are based on the immunoglobulin protein produced by the myeloma cell. About 20 out of 100 people with myeloma 20 do not produce complete immunoglobulins. Additional genetic testing of a patient s myeloma cells can be done to determine risk based on common genetic myeloma features. In myeloma patients these numbers are typically.

Multiple myeloma has different types and subtypes. Igm ige and igd types have one much lower incidence. The two types of light protein chains are kappa κ and. The serum free light chain test can be used to determine light chain levels of disease so patients will want to track their light chain numbers.

The light chains can show up in the urine. Healthy blood cells produce antibodies that help to fight infection. Light chain myeloma also known as light. 65 of patients with myeloma have an igg type.

There are 2 types of light chains called kappa and lambda. The various immunoglobulins have different functions in the body. Bottom line in myeloma therapy in patients with multiple myeloma the free light chain assay is important in predicting response to therapy and for predicting early signs of. Multiple myeloma is a form of cancer that afflicts human bone marrow and blood cells.

Light chain myeloma sometimes called bence jones myeloma. The second most common type is the iga myeloma also in combination with any of the two light chains. They only produce part of the immunoglobulin called the light chain. But myeloma cells can cause fatigue easy bleeding and lowered resistance to infections.